Mentor:
Education:
2011 B.S. Bates College, Lewiston, ME.
Awards:
2009 POLYED Undergraduate Award for Achievement in Organic Chemistry (Bates College)
Research Experience:
2010-2011 Undergraduate Research in Organic Synthesis: In the lab of Jennifer Koviach-Cote, I worked on the total synthesis of natural products with a specific focus on the application of the Sonogashira reaction.
2008-2009 Undergraduate Research: In the lab of Matthew Cote, worked on the synthesis of gold nanorods and atomic force microscopy.
Current Research Activities:
I am studying the synthesis and use of novel hypervalent iodine reagents for the use in the total synthesis of biologically active natural products. My interest specifically is in improving oxidative phenolic couplings, spirolactonizations, and nucleophilic dearomatizations. A vast number of natural product syntheses can be improved by the reduction of steps and introduction of chirality thereby eliminating the necessity for resolution or additional synthetic operations.
Poster:
Asymmetric oxidative cyclizations for the use in the synthesis of biologically active natural products; 2013 Keck Biomembrane Retreat, Ithaca, NY, June 25-27, 2013
Publications:
Moschitto, M. J., Vaccarello, D. N., and Lewis, C. A. (2014) Regiodivergent Addition of Phenols to Allylic Oxides: Control of 1,2- and 1,4-Additions for Cyclitol Synthesis, Angew. Chem. Int. Ed. Engl. 54, 2142-2145. PubMed
Moschitto, M. J., Anthony, D. R., and Lewis, C. A. (2015) Syntheses of Arnottin I and Arnottin II, J. Org. Chem. 80, 3339-3342. PubMed
Vaccarello, D. N., Moschitto, M. J., and Lewis, C. A. (2015) Regiodivergent Addition of Phenols to Allylic Oxides, J. Org. Chem. 80, 5252–5259. PubMed