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Emily Perregaux

Emily Perregaux

Mentor: Matt DeLisa


B. S. Biology (minor chemistry; Magna Cum Laude), Houghton College


Houghton College President’s List Fall 2010, Fall 2012
Houghton College Chamberlain Presidential Scholarship (2009-2012)
Houghton College Ken Boon Academic Scholarship (2012)
Sigma Zeta National Science and Mathematics Honor Society Member

Research Experience:

Project: Alternative Energy Sources for Transportation
Principle Investigator: Dr. Mark Yuly, First Year Honors Program
Houghton College, Sept. 2009 – Sept. 2011

Project: Characterization of Mitochondrial Transhydrogenase in Manduca Sexta
Principle Investigator: Dr. Kurt P. Vandock
Houghton College, Sept. 2010 – Dec. 2012

Project: Synthesis of Glycosyl Thiols
Principle Investigator: Dr. Kurt P. Vandock
Houghton College, Sept. 2011 – Dec. 2012

Intern, Formulations Department
Regeneron Pharmaceuticals, Inc., May 2012 – Aug. 2012

Research Associate, Formulations Department
Regeneron Pharmaceuticals, Inc., Jan. 2013 – Aug. 2013

Current Research Activities:

The objective of my research is to create a robust strategy for the rapid discovery and quantitative characterization of selective, high-affinity antibodies against defined glycan structures or glycan-polypeptide determinants of biomedical importance. Central to this effort is the use of glycoengineered Escherichia coli cells that can furnish large quantities of structurally uniform glyco-antigens, such as tumor-associated carbohydrate antigens (TACAs). By immobilizing these homogenous TACAs to solid supports, it will be possible to isolate synthetic antibodies from phage libraries that specifically recognize distinct glycan structures and thus could serve as diagnostic tools or immunotherapeutics for cancer.


Vandock K, Perregaux E, Consiglio B. 2013. Effects of 20-hydroxyecdysone on the reversible mitochondrial transhydrogenase in the tobacco hornworm, Manduca sexta. J. Insect Science, 13:154. PMC

Perregaux E, van der Rijst N, Vandock K. 2013. Effects of caffeine on the growth and post-embryonic development in Manduca sexta. J. Undergraduate Research Scholarly Excellence 4:1. URL

Ollis, A. A., Chai, Y., Natarajan, A., Perregaux, E., Jaroentomeechai, T., Guarino, C., Smith, J., Zhang, S., and DeLisa, M. P. (2015) Substitute sweeteners: diverse bacterial oligosaccharyltransferases with unique N-glycosylation site preferences, Sci. Rep. 5, 15237. PubMed

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